Just caught an unusual behavior with the OpenDNS name resolution. I tried to launch Desktop Tower Defense (yes, I'm still addicted, I could not let go just yet). OpenDNS told me www.handdrawngames.com wasn't reachable. After refreshing the cache, the problem persisted. They directed me to a third-party tool (DNSstuff.com) which gives a nice resume of one site's DNS status. Turns out one of the name servers gives a "No A record" while the other does return an IP. If I were using my ISP's DNS servers, it would probably give me that IP as the resolved name, even if records do not match. But OpenDNS is more severe. If records do not match, even if only one gives an IP, it fails and displays the usual "not loading" page.
I'm no DNS guru, but if I were OpenDNS, I'd see if I could not offer the user to try that IP from the "not loading" page, something like "Records seems inconsistent. Click here to try anyway".